A Rapid and Facile Synthesis of 4 , 6 - Dimethylpyrimidine - 2 ( 1 H ) - One
نویسنده
چکیده
A rapid and efficient synthesis of 4,6-Dimethylpyrimidine-2(1H )-one has been carried out from acetylacetone and urea in dry media in the presence of an environmentally friendly non-corrosive, non-toxic and recyclable catalyst in 85% yield under microwave irradiation conditions.
منابع مشابه
Facile and Rapid Synthesis of 3,4-Dihydropyrimidin-2(1H)-one Derivatives Using [Et3NH][HSO4] as Environmentally Benign and Green Catalyst
5-acetyl-6-methyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones were synthesized in good to excellent by one-pot three-component Biginelli condensation in the presence of ammonium salt [Et3NH][HSO4] as an inexpensive and green catalyst under solvent-free conditions. High yields, short reaction time, easy work-up, a green environment which requires no toxic o...
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